Lisa Rosenbaum.

Lisa Rosenbaum, M.D .: Transitional Enduring or Chaos Harm? The EHR and the Disruption of Medicine A decade ago, a primary care physician I undone admired seemed to come. His performance had derived not really from rushing between sufferers but from understanding them therefore well that his charting was effortless and fast. But he became distracted all of a sudden, losing his hold on the facts of his individuals’ lives. He slumped around, shirt half-untucked, perpetually pulling a yellowed handkerchief from his pocket to wipe his perspiring forehead.

Mental retardation was unexplained in these patients despite regular investigations, including karyotyping, subtelomeric fluorescence in situ hybridization analysis, or comparative genomic hybridization targeting regions connected with known syndromes, molecular testing for the common expansion mutation in FMR1, and computed tomography or magnetic resonance imaging of the brain. We also studied 3 group of other subjects, including 142 subjects with nonsyndromic autism spectrum disorders, 143 subjects with schizophrenia, and 190 healthy control subjects matched for ancestral origin. The subjects in every three series were generally of French Canadian or European origin .