Kainer, M.B., B.S., M.P.H., Ruth Lynfield, M.D., Meghan Maloney, M.P.H., Laura McAllister-Hollod, M.P.H., Joelle Nadle, M.P.H., Susan M. Ray, M.D., Deborah L. Thompson, M.D., M.S.P.H., Lucy E. Wilson, M.D., and Scott K. Fridkin, M.D. Presently, no U.S. Surveillance system can offer estimates of the burden of all types of such attacks across acute care patient populations. Most hospitals limit reporting to device-associated infections, selected surgical-site attacks, and infections due to Clostridium difficile and methicillin-resistant Staphylococcus aureus .We excluded individuals whose symptoms fit these criteria but who had various other clinical or laboratory-verified diagnoses. We defined a laboratory-confirmed case as meeting one or more of the following criteria: the isolation of SFTSV from the patient’s serum, the recognition of SFTSV RNA in the patient’s serum during the acute stage of the illness, or the detection of seroconversion or an elevation by way of a element of four in serum IgG antibodies against SFTSV about enzyme-linked immunosorbent assay , indirect immunofluorescence assay, or neutralization assessment in serum obtained through the convalescent phase.
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