The syndrome was not associated with improved mortality among patients undergoing cord-blood HSCT. A significant proportion of patients at our middle received sirolimus and tacrolimus for GVHD prophylaxis; nevertheless, the cord colitis syndrome was determined in sufferers who didn’t receive either agent. Sufferers with a history of grade 2 or higher acute GVHD were much more likely to have the cord colitis syndrome than were sufferers with grade 1 GVHD or no GVHD. In all the sufferers with GVHD who acquired the cord colitis syndrome, the GVHD resolved clinically prior to the syndrome developed. However, the real number of sufferers in the cohort who had had acute GVHD was small, so it is hard to interpret the need for this observation.The report was published online Aug. 24 in the Journal of the American College of Cardiology. For the study, Sanders and colleagues assigned 308 patients with atrial fibrillation to 1 of three groups based on their fitness level: low, adequate, or high fitness. All acquired a body mass index of 27 or more, meaning they were overweight or obese. The groupings were followed for approximately four years to observe how their level of fitness affected the recurrence of the abnormal heartbeat. Patients had been also offered a doctor-led weight loss and exercise program. After four years of follow-up, 84 % in the high fitness group no had atrial fibrillation much longer, weighed against 76 % in the adequate group and 17 % in the low fitness group, the researchers found.
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