All three drugs potentially block the effects of VEGF. Wet age-related macular degeneration is the third most common cause of blindness worldwide. It affects around 2.3 percent of over-65s in Europe. In the UK around 26,000 people develop it each year and 245, 000 are blind or visually impaired due to it. After a thorough examination of published clinical trial data, DTB concludes that there is good proof that both ranibizumab and pegaptanib prevent further deterioration in eyesight in most individuals.Related StoriesUCSF-led experts map out melanoma's genetic trajectoriesTesting amniotic fluid could instruction doctors to make delivery planning decisions for preterm birthsDisclosing genetic risk for CHD results in decrease low-density lipoprotein cholesterolThe researchers looked at 457 pairs of twins from the Colorado Learning Disabilities Research Center twin study – an ongoing study of the sources of reading disabilities, ADHD, and related disorders. Dr Erik Willcutt and colleagues compared groups of participants with and without RD and ADHD, using a variety of assessments to measure general cognitive capability, processing speed, language and reading skills, and then analysed results from pairs of twins within those combined groupings to look for the genetic factors behind any correlations.