She added that the %age of sufferers who discontinued treatment owing to toxicity was not too not the same as the proportion mentioned in the interim evaluation, at 16 percent for the dabrafenib plus trametinib arm and 14 percent for the vemurafenib arm . Licensed from medwireNews with authorization from Springer Health care Ltd. All rights reserved. Neither of these ongoing parties endorse or recommend any commercial products, services, or equipment.. 2-year advanced melanoma survival benefit with dabrafenib, trametinib combination By Shreeya Nanda, Senior medwireNews Reporter Updated results from the COMBI-v trial display significantly improved overall and progression-free survival with first-line dabrafenib in addition trametinib weighed against vemurafenib in patients with advanced melanoma.There's lots of money in pharmaceuticals for treating chronic ailments such as diabetes, but if we are to earn the competition against bacteria, we need to bring new antibiotics into enjoy. Nature is a superb starting place for developing medicines – two-thirds of all new pharmaceuticals derive from natural chemicals, concludes Tim Holm Jakobsen.. Adamas Pharmaceuticals forges contract with U.S. Naval Wellness Research Middle for evaluating triple mixture antiviral drug Adamas Pharmaceuticals, Inc., a held company privately, announced today that it has entered into a Cooperative Research and Development Contract with america Naval Health Research Middle for preclinical research evaluating Adamas’ triple mixture antiviral drug therapy for influenza A, including novel influenza A/H1N1.